Cat No.
CEI-0516
Description
Nexturastat A is an aryl urea derivative that acts as a potent and highly selective inhibitor of histone deacetylase 6 (HDAC6) (IC50 = 5.02 ± 0.60 nM). Displays 600-, 1380-, 1330-, 1870-, -2330, -888, -190, -1340, -1510, and -1020-fold selectivities over HDAC1, HDAC2, HDAC3, HDAC4, HDAC5, HDAC7, HDAC8, HDAC9, HDAC10, and HDAC11, respectively. Nexturastat A also displays antiproliferative effects against melanoma cells.
Product_Overview
A potent HDAC6 inhibitor
Targets
HDAC6
Chemical Name
4-((1-butyl-3-phenylureido)methyl)-N-hydroxybenzamide
M.Wt
672.81
Purity
>95% by HPLC
Appearance
Liquid
Formulation
DMSO (12 mM)
Storage
-20 centigrade
Shipping Conditions
Gel pack
Handling
Protect from light and moisture
Usage
For Research Use Only! Not For Use in Humans.
