Cat No.
CEI-0518
Description
Cell-permeable. A synthetic derivative of the natural product Cyclopamine that acts as a specific inhibitor of Smoothened (Smo) and Sonic hedgehog (Shh) intracellular signaling (IC???=?20 nM in the Shh-LIGHT2 assay).
Alias
KAAD-cyclopamine
Synonyms
KAAD-cyclopamine
CAS No.
306387-90-6
Product_Overview
A Smoothened (Smo) antagonist
Targets
Hh
Chemical Name
3-Keto-N-(aminoethyl-N’-aminocaproyldihydrocinnamoyl)cyclopamine
M.Wt
316.85
Purity
>98% by HPLC
Appearance
Yellow solid
Solubility
DMSO (100 mM) or EtOH (10 mM)
Storage
-20 centigrade
Shipping Conditions
Gel pack
Handling
Protect from moisture
Usage
For Research Use Only! Not For Use in Humans.
