Cat No.
CEI-0539
Description
A cell-permeable prolyl 4-hydroxylase (P4H) inhibitor; inhibits hypoxia-inducible factor α (HIF-α) prolyl hydroxylase (HIF-PH). Increases levels of HIF-1α; promotes cell survival under hypoxic conditions. DMOG posseses neuroprotective effect on NFG deprived cell cultures through preservation of glucose metabolism. DMOG also attenuates myocardial injury in a rabbit ischemia reperfusion model.
Alias
N-(2-Methoxy-2-oxoacetyl)glycine methyl ester
Synonyms
N-(2-Methoxy-2-oxoacetyl)glycine methyl ester
CAS No.
89464-63-1
Product_Overview
A hypoxia-inducible factor α (HIF-α) prolyl hydroxylase (HIF-PH) inhibitor
Targets
HIF-PH
M.Wt
342.37
Purity
>95%
Appearance
White to Off-white Solid
Solubility
DMSO (5 mg/ml) or EtOH (0.5 mg/ml)
Storage
-20 centigrade
Shipping Conditions
Gel Pack
Handling
Protect from light and moisture
Usage
For Research Use Only! Not For Use in Humans.
