Cat No.
CEI-0532
Description
A cholesterol lowering drug and a competitive inhibitor of HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase (IC50 = 154 nM) a rate limiting enzyme in cholesterol synthesis. Blocks the production of mevalonate, a critical compound in the production of cholesterol and isoprenoids. In addition to inhibiting cholesterol synthesis, atorvastatin reduces the production of low-density lipoprotein (LDL).
CAS No.
134523-00-5
Product_Overview
A potent HMG-CoA reductase inhibitor
Targets
HMG-CoA
Chemical Name
2-?(4-?fluorophenyl)-?βR,?δR-?dihydroxy-?5-?(1-?methylethyl)-?3-?phenyl- ?4-?[(phenylamino)carbonyl]-?1H-?pyrrole-?1-?heptanoic acid
M.Wt
164.28
Purity
>98%
Appearance
White solid
Solubility
DMSO (15 mg/ml) and H?O (1 mg/ml)
Storage
+4C
Shipping Conditions
RT
Handling
Protect from air and moisture
Usage
For Research Use Only! Not For Use in Humans.
