Cat No.
CEI-0717
Description
A slow-releasing, water-soluble hydrogen sulfide (H?) donor. Displays vasodilator and antihypertensive activity in rats in both acute (L-NAME-induced) or chronic (spontaneously hypertensive) hypertension models. Inhibits LPS-induced release of various proinflammatory mediators (such as IL-1β, IL-6, TNF-α, nitric oxide (NO) and PGE2) in RAW264.7 cells. Increases the synthesis of the anti-inflammatory chemokine IL-10 through NF-κB, ATF-2 and HSP27 dependent pathways in RAW264.7 cells.
Alias
p-?Methoxyphenyl)morpholino-?phosphinodithioic acid
Synonyms
p-?Methoxyphenyl)morpholino-?phosphinodithioic acid
CAS No.
106740-09-4
Product_Overview
A slow-releasing, water-soluble hydrogen sulfide (HzS) donor
Targets
Proinflammatory mediators
Chemical Name
p-?Methoxyphenyl)morpholino-?phosphinodithioic acid
M.Wt
367.3
Purity
>99%
Appearance
White solid
Solubility
DMSO ( 20 mg/ml)
Storage
-20 centigrade
Shipping Conditions
RT
Handling
Protect from light and moisture
Usage
For Research Use Only! Not For Use in Humans.
