Cat No.
CEI-0540
Description
A potent immunosuppresant and in vitro T cell proliferation blocker. It disrupts calcineurin-mediated signal transduction in T-lymphocytes. It interacts with its FK506-binding protein-12 (FKBP-12), leading to increase in the release of sarcoplamic reticulum-derived calcium. FK506 and rapamycin, but not cytosporin inhibit aldosterone-stimulated sodium transport in A6 cells.
Alias
Tacrolimus
Synonyms
Tacrolimus
CAS No.
104987-11-3
Product_Overview
A potent immunosuppresant
Targets
immunosuppresant
Chemical Name
Tacrolimus
M.Wt
805
Purity
>98%
Appearance
White solid
Solubility
DMSO (>1 mg/ml) and EtOH (>1 mg/ml)
Storage
-20 centigrade
Shipping Conditions
Gel pack
Handling
Protect from moisture. Tumor promoter
Usage
For Research Use Only! Not For Use in Humans.
