Cat No.
CEI-1143
Description
GPLG0634 is a novel inhibitor of JAK1 and JAK2 with IC50 of 10nM and 28nM respectively in vitro.
Abbr
GPLG0634(JAK1, JAK2 )
Alias
JAK1A, JAK1B, JTK3
Synonyms
JAK1A, JAK1B, JTK3
CAS No.
1206161-97-8
IC50
10nM, 28nM
Targets
JAK1, JAK2
Chemical Name
Cyclopropanecarboxamide, N-[5-[4-[(1,1-dioxido-4-thiomorpholinyl)methyl]phenyl][1,2,
4]triazolo[1,5-a]pyridin-2-yl]-
M.Wt
425.5
Purity
> 95%
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
Storage
4 centigrade
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
