Cat No.
CEI-1071
Description
WP1066 is a novel inhibitor of JAK2 and STAT3 with IC50 of 2.30 μM and 2.43 μM in HEL cells; shows activity to JAK2, STAT3, STAT5, and ERK1/2 not JAK1 and JAK3.
Abbr
WP1066(JAK2, STAT3)
Alias
JTK10, THCYT3
Synonyms
JTK10, THCYT3
CAS No.
857064-38-1
IC50
2.3 μM, 2.43 μM
Targets
JAK2, STAT3
Chemical Name
(S,E)-3-(6-bromopyridin-2-yl)-2-cyano-N-(1-phenylethyl)acrylamide
M.Wt
356.22
Purity
0.9949
Solubility
DMSO 72 mg/mL
Water <1 mg/mL
Ethanol <1 mg/mL
Storage
2 years -20 centigrade Powder
2 weeks4centigradein DMSO
6 months-80centigradein DMSO
