Cat No.
CEI-0544
Description
An organo-selenium compound that displays potent antioxidant properties. Acts as a glutathione peroxidase (GPX) mimic as well as being an excellent scavenger of peroxynitrite. The glutathione peroxidase-like activity of ebselen inhibits cyclooxygenase (COX) and lipoxygenases at micromolar concentrations. Also acts as a histone-lysine demethylase (HKDM) inhibitor. Inhibits JARID1B protein with an IC50 of 5.17 μM.
CAS No.
60940-34-3
Product_Overview
A glutathione peroxidase (GPx) mimetic and a peroxynitrite scavenger
Targets
KDM5B
Chemical Name
2-Phenyl-1,2-benzisoselenazol-3-(2H)-one
M.Wt
292.12
Purity
>98% by TLC
Appearance
White solid
Solubility
DMSO (25 mg/ml)
Storage
-20 centigrade
Shipping Conditions
Gel pack
Handling
Protect from air, light and moisture
Usage
For Research Use Only! Not For Use in Humans.
