Cat No.
CEI-1135
Description
AMG-1 is a potent inhibitor of human c-Met and RON with IC50 of 4 and 9 nmol/L respectively.
Abbr
AMG-1(MET, MST1R)
Alias
AUTS9, HGFR, RCCP2, c-Met
Synonyms
AUTS9, HGFR, RCCP2, c-Met
CAS No.
913376-84-8
IC50
4nmol/L, 9 nmol/L
Targets
c-Met, RON
Chemical Name
N-(3-fluoro-4-(7-methoxyquinolin-4-yloxy)phenyl)-1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide
M.Wt
556.58
Purity
> 95%
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
Storage
4 centigrade
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
