Cat No.
CEI-0563
Description
A plant alkaloid that arrests the cell cycle in G2/M phase by blocking mitotic spindle formation. Inhibits normal microtubule assembly and causes aberrant tubulin polymerization. Blocks binding of tubulin to microtubule proteins. Induces apoptosis. Triggers Raf-1 activation, phosphorylation of Bcl-2 family proteins and induction of p53 expression. Cancer chemotherapeutic agent.
Alias
Vincaleukoblastine sulfate salt; VLB
Synonyms
Vincaleukoblastine sulfate salt; VLB
CAS No.
143-67-9
Product_Overview
A tubulin polymerrization inhibitor
Targets
MGMT
M.Wt
271.27
Purity
>98% by HPLC
Appearance
White solid
Solubility
DMSO (100 mM)
Storage
RT
Shipping Conditions
RT
Handling
Protect from air and light
Usage
For Research Use Only! Not For Use in Humans.
