Cat No.
CEI-0569
Description
Cell-permeable. A macrophage migration inhibitory factor (MIF) antagonist. ISO-1 inhibits MIF pro-inflammatory activities by targeting MIF tautomerase activity. Also inhibits tumor necrosis factor (TNF) release from macrophages isolated from LPS- treated wild type mice but has no effect on cytokine release from MIF deficient macrophages
CAS No.
478336-92-4
Product_Overview
A migration inhibitory factor (MIF) antagonist
Targets
MIF
Chemical Name
(S,R)-3-(4-Hydroxyphenyl)-4,5-dihydro-5-isoxazole acetic acid, methyl ester
M.Wt
507.68
Purity
>98% by HPLC
Appearance
White to off-white solid
Solubility
DMSO (40 mg/ml) or EtOH (40 mg/ml)
Storage
-20 centigrade
Shipping Conditions
Gel pack
Handling
Protect from air and light
Usage
For Research Use Only! Not For Use in Humans.
