Cat No.
CEI-0580
Description
A potent, irreversible, and specific inhibitor of the peroxidation activity of myeloperoxidase (MPO; IC?sub>50 = 300 nM). Does not affect catalase or glutathione peroxidase activities. Also displays no effect on the production of superoxide by neutrophils. Shown to inhibit H 2 O 2 -induced apoptosis in HL-60, human leukemia cells.
Alias
4-Aminobenzoic hydrazide; MPO Inhibitor; 4-ABH
Synonyms
4-Aminobenzoic hydrazide; MPO Inhibitor; 4-ABH
CAS No.
5351-17-7
Product_Overview
A potent myeloperoxidase (MPO) inhibitor
Targets
MPO
M.Wt
223.35
Purity
>97% by HPLC
Appearance
Yellow to beige solid
Solubility
DMSO or EtOH
Storage
-20 centigrade
Shipping Conditions
Gel pack
Handling
Protect from air and light
Usage
For Research Use Only! Not For Use in Humans.
