Cat No.
CEI-0575
Description
A broad spectrum matrix metalloprotease (MMP) inhibitor with IC50 values of 3, 5, 6, 9 and 13 nM for MMP-9, MMP-1, MMP-2, MMP-14 and MMP-7 respectively. It covalently binds to the zinc(II) ion in the active site of MMPs, thereby inhibiting the action of MMPs, inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis.
Alias
BB-2516; TA-2516; Marimistat
Synonyms
BB-2516; TA-2516; Marimistat
CAS No.
154039-60-8
Product_Overview
A broad spectrum MMP inhibitor
Targets
MPTP
Chemical Name
(2S,3R)-N4-[(1S)-2,2-Dimethyl-1-[(-[(methylamino)carbonyl]propyl]-N1,2-dihydroxy-3-(2-methylpropyl)butanediamide
M.Wt
357.41
Purity
>99% by HPLC
Appearance
White crystalline solid
Solubility
DMSO (25 mg/ml) or H2O (20 mg/ml)
Storage
-20 centigrade
Shipping Conditions
RT
Handling
Protect from air and moisture
Usage
For Research Use Only! Not For Use in Humans.
