Cat No.
CEI-0122
Description
Everolimus (RAD001) can inhibit FKBP12 with IC50 of 1.6-2.4 nM.
Alias
Certican, Zortress, Afinitor
Synonyms
Certican, Zortress, Afinitor
CAS No.
159351-69-6
Targets
mTOR
Chemical Name
23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine, rapamycin deriv
M.Wt
958.22
Purity
>99%
Solubility
DMSO 30 mg/mL Water
Storage
2 years at -20centigrade Powder
In vitro
As an mTOR inhibitor, everolimus (RAD001) can FKBP12 with IC50 of 1.6-2.4 nM. RAD001 inhibits tumor cell growth directly, blocks angiogenesis, and suppresses the immune response.
