Cat No.
CEI-1183
Description
A potent antagonist highly selective for AChRs with α7 subunit (Ki = 1.4 nM for α7 subunit and > 40 nM for α4β2 and α6β2 receptors). Frequently used in assessing the functional roles of AChRs with α7 subunit in brain functions and disorders (i.e. inflammatory and chronic neuropathic pain and parkinsonian neurodegeneration).
Abbr
MLA
Synonyms
AChR Receptor Antagonist, Methyllycaconitine Citrate, alpha7beta2 recptor Antagonist, Methyllycaconitine Citrate, Methyllycaconitine; α7-Nicotinic Receptor Antagonist, Methyllycaconitine Citrate, Neuronal Nicotinic Receptor Antagonist, Methyllycaconitine Citrate
CAS No.
21019-30-7
Targets
α7 nAChR
Ki Data
1.4nM
Purity
>97% by HPLC
Appearance
White solid
Solubility
H2O
Storage
-20 centigrade
Stability
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Shipping Conditions
Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
