Cat No.
CEI-1182
Description
α-Bungarotoxin is a snake venom-derived toxin that irreversibly binds nicotinic acetylcholine receptors (Ki = ~ 2.5 μM in rat) present in skeletal muscle, blocking action of acetylcholine at the postsynaptic membrane and leading to paralysis. It has been widely used to characterize activity at the neuromuscular junction, which has numerous applications in neuroscience research.
Abbr
α-BTX
Synonyms
α-BTX, α-Bgt
CAS No.
11032-79-4
Targets
α7, α1/β1/γ/δ nAChR, GABA(A) receptor subtypes
M.Wt
7984.3
InChi
1S/C338H531N97O105S11/c1-32-165(17)216(139-436)426-427-258(164(15)16)319(524)410-229-152-548-545-149-226-303(508)390-207(123-180-83-87-185(450)88-84-180)288(493)377-195(73-52-109-357-337(350)351)276(481)375-191(67-40-46-103-340)274(479)382-201
InChi Key
OKKRKMKPOYDAKJ-RRDFZLDRSA-M
Purity
>99%
Appearance
A white to off-white solid
Solubility
Soluble in aqueous buffers
Storage
-20 centigrade
Stability
1 years
Shipping Conditions
Room temperature in continental US; may vary elsewhere
