Cat No.
CEI-0584
Description
A potent necroptosis inhibitor. Displays higher activity in inhibiting necroptosis in Jurkat cells than Nec-1 (EC?? = 210 nM versus EC?? = 490 nM), as well as showing no nonspecific cytotoxicity at high concentrations (~100 mM). More useful for in-cell and in vivo experiments compared to Nec-1.
Alias
7-Cl-O-Nec-1
Synonyms
7-Cl-O-Nec-1
Product_Overview
A potent necroptosis inhibitor
Targets
Necroptosis
Chemical Name
5-((7-Cl-1H-indol-3-yl)methyl)-3-methylimidazolidine-2,4-dione)
M.Wt
763.78
Purity
>99% by HPLC
Appearance
Liquid
Formulation
DMSO (3 mM)
Storage
-20 centigrade
Shipping Conditions
Gel pack
Handling
Protect from light and moisture
Usage
For Research Use Only! Not For Use in Humans.
