Cat No.
CEI-1121
Description
GNE-490 is a highly selective pan-PI3K inhibitor and demonstrates selectivity over mTOR. It has good pharmacokinetic (PK) parameters and demonstrates knock down of pathway markers in vivo. This compound represents an excellent tool to further evaluate the therapeutic potential of a PI3K inhibitor in the treatment of cancer.
Abbr
GNE-490(pan-PI3K )
CAS No.
1033739-92-2
Product_Overview
pan-PI3K inhibitor
Targets
pan-PI3K
Chemical Name
2-(2-(2-amino-4-methylpyrimidin-5-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)propan-2-ol
M.Wt
386.47
Purity
> 95%
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
Storage
-20 centigrade
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
