Cat No.
CEI-0417
Description
Cell-permeable. A potent, cAMP-specific phosphodiesterase (PDEIII ) inhibitor (IC50 = 0.45 and 1.0 μM for PDEIIIA and PDEIIIB, respectively). It inhibits other PDE isoforms at much higher concentrations. Milrinone has positive inotropic (stimulates cardiac muscle contractions) and vasodilatory effects when administered in vivo.
Alias
WIN 47, 203
Synonyms
WIN 47, 203
CAS No.
78415-72-2
Product_Overview
A cAMP-specific phosphodiesterase (PDEIII ) inhibitor
Targets
cAMP-specific phosphodiesterase (PDEIII )
Chemical Name
1,?6-?dihydro-?2-?methyl-?6-?oxo-?[3,?4'-?bipyridine]-?5-?carbonitrile
M.Wt
396.31
Purity
>98% by HPLC
Appearance
Yellow solid
Solubility
DMSO (100 mM)
Storage
-20 centigrade
Shipping Conditions
Gel pack
Handling
Protect from air and light
Usage
For Research Use Only! Not For Use in Humans.
