Cat No.
CEI-0616
Description
Apremilast is a potent PDE4 (phosphodiesterase 4) inhibitor (IC50 = 74 nM). It reduces TNF-α production in human synovial cells and significantly suppresses experimental arthritis.
CAS No.
608141-41-9
Product_Overview
A potent PDE4 (phosphodiesterase 4) inhibitor
Targets
PDE1a, PDE2A, PDE3A, PDE4A, PDE5A
Chemical Name
N-{2-[(1S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide
M.Wt
602.8
Purity
>95% by TLC
Appearance
Yellow solid
Solubility
DMSO (25 mg/ml) or EtOH (25 mg/ml)
Storage
-20 centigrade
Shipping Conditions
Gel pack
Handling
Protect from air and light
Usage
For Research Use Only! Not For Use in Humans.
