Cat No.
CEI-0892
Description
CP 673451 is a highly selective PDGFR inhibitor, equipotent to PDGFR-α/β with IC50 of 10 nM/1 nM, >250-fold more selective for PDGFR than c-Kit, VEGFR1/2, Tie-2, FGFR-2.
Alias
CP673451
Synonyms
CP673451
CAS No.
343787-29-1
IC50
10 nM; 1 nM
Targets
PDGFR-α/β
Chemical Name
1-(2-(5-(2-methoxyethoxy)-1H-benzo[d]imidazol-1-yl)quinolin-8-yl)piperidin-4-amine
M.Wt
417.5
Solubility
DMSO 42 mg/mL; Water <1 mg/mL; Ethanol 4 mg/mL
Storage
2 years -20 centigrade Powder; 2 weeks 4 centigrade in DMSO; 6 months -80 centigrade in DMSO.
