Cat No.
CEI-1103
Description
PIK-75, free base is a PI3K inhibitor displaying selectivity for the p110α isoform (IC50 6nM). PIK-75 blocks the phosphorylation of PKB induced by insulin.
Abbr
PIK-75(PIK3CA)
Alias
CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha
Synonyms
CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha
CAS No.
372196-67-3
Product_Overview
PI3K inhibitor selectivity for the p110α isoform
Targets
p110α
Chemical Name
(Z)-N'-((6-bromoH-imidazo[1,2-a]pyridin-3-yl)methylene)-N,2-dimethyl-5-nitrobenzenesulfonohydrazide
M.Wt
452.28
Purity
> 95%
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
Storage
4 centigrade
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
