Cat No.
NATE-0158
Description
The enzyme catalyses electron transfer to cytochrome P450. This system plays a major role in detoxification of drugs and xenobiotics, activation of carcinogens, and metabolism of endogenous substrates such as steroids.
Abbr
CPR, Native (Rabbit)
Alias
CPR
Source
Rabbit liver
Species
Rabbit
Form
buffered aqueous glycerol solution. Solution in 30 mM potassium phosphate buffer, pH 7.7, and 0.1 mM EDTA containing 50% (v/v) glycerol.
Enzyme Commission Number
EC 1.6.2.4
Bio-activity
25-75 units/mg protein (Bradford)
CAS No.
9039-06-9
Molecular Mass
mol wt ~80 kDa
Purification
~90% (SDS-PAGE)
Unit Definition
One unit will catalyze the reduction of 1.0 μmole of cytochrome c by NADPH per min at pH 7.7 at 30°C.
Synonyms
EC 1.6.2.4; NADPH:ferrihemoprotein oxidoreductase; NADPH:hemoprotein oxidoreductase; NADPH:P450 oxidoreductase; P450 reductase; CPR; 9039-06-9; FAD-cytochrome c reductase; NADPH-dependent cytochrome c reductase; NADPH:P-450 reductase
