Cat No.
NATE-0448
Description
Malic dehydrogenase (MDH) exists as two isoforms within eukaryotic cells, one that is expressed in the mitochondria and functions in the TCA cycle and one in the cytoplasm that converts malate from the mitochondria back into oxaloacetate.
Abbr
MDH, Native (Thermus flavus)
Alias
malic enzyme
Species
Thermus flavus
Form
lyophilized powder; Contains dextran
Enzyme Commission Number
EC 1.1.1.37
Bio-activity
> 50 units/mg solid
CAS No.
9001-64-3
Unit Definition
One unit will convert 1.0 μmole of oxalacetate and β-NADH to L-malate and β-NAD per min at pH 7.5 at 25°C.
Applications
Malic dehydrogenase has been used in a study to assess electron transport chain activity in mit ochondria from human skeletal muscle. It has also been used in a study to investigate activities of enzymes and ammonia in serum of rats with fluoride hyperglycemia.
Synonyms
malic dehydrogenase; L-malate dehydrogenase; NAD-L-malate dehydrogenase; malic acid dehydrogenase; NAD-dependent malic dehydrogenase; NAD-malate dehydrogenase; NAD-malic dehydrogenase; malate (NAD) dehydrogenase; NAD-dependent malate dehydrogenase; NAD-specific malate dehydrogenase; NAD-linked malate dehydrogenase; MDH; L-malate-NAD+ oxidoreductase; EC 1.1.1.37; 9001-64-3
