Cat No.
NATE-1064
Description
Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The enzyme is a homodimer. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification.
Abbr
XDH, Native (Microorganism)
Alias
XDH
Species
Microorganism
Form
Liquid
Enzyme Commission Number
EC 1.17.1.4
Bio-activity
> 100 U/mL
Appearance
Brownish solution
Molecular Mass
240 kDa
pH Stability
6.5 - 9.5
Isoelectric point
pH 4.5±0.2
Unit Definition
One unit is defined as the amount of enzyme which converts 1 μmole of xanthine to uric acid per minute at 37°C under the conditions specified in the assay procedure.
Optimum pH
8.5
Optimum temperature
55°C
Thermal stability
Stable at 60°C and below (pH 7.5, 15 mins)
Applications
Useful for the enzymatic determiantion of inorganic phosphate.
Synonyms
xanthine dehydrogenase; NAD+-xanthine dehydrogenase; xanthine-NAD+ oxidoreductase; xanthine/NAD+ oxidoreductase; xanthine oxidoreductase; XDH; EC 1.17.1.4
