Abl Kinase Mutant active human, recombinant

 
 
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发货 北京
过期 长期有效
更新 2026-10-26 09:54
 

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详细说明
Cat No.
NATE-0013
Description
Abelson murine leukemia viral oncogene homolog 1 also known as ABL1 is a protein that, in humans, is encoded by the ABL1 gene (previous symbol ABL) located on chromosome 9. c-Abl is sometimes used to refer to the version of the gene found within the mammalian genome, while v-Abl refers to the viral gene.
Abbr
ABL1, Recombinant (Human)
Alias
ABL1; ABL; c-ABL; v-abl
Source
Baculovirus infected Sf9 cells
Species
Human
Form
aqueous solution
Molecular Mass
mol wt 33 kDa
Stability
?70°C
Gene Name
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase [Homo sapiens]
Synonyms
ABL1; JTK7; c-ABL; p150; Abl Kinase; ABL; bcr/abl; c-ABL1; v-abl
GeneID
25
mRNA Refseq
NM_007313
Protein Refseq
NP_009297
MIM
189980
UniProt ID
P00519
Chromosome Location
9q34.1
Pathway
Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Axon guidance, organism-specific biosystem; CDO in myogenesis, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem
Function
ATP binding; DNA binding; SH3 domain binding; actin monomer binding; kinase activity; magnesium ion binding; manganese ion binding; mitogen-activated protein kinase binding; nicotinate-nucleotide adenylyltransferase activity; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; proline-rich region binding; protein C-terminus binding; protein binding; protein tyrosine kinase activity; receptor activity
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