Cat No.
NATE-0141
Description
In the cells, the "cytosolic" CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type). There are, therefore, three different isoenzymes:CK-MM, CK-BB and CK-MB. The genes for these subunits are located on different chromosomes:B on 14q32 and M on 19q13. In addition to those three cytosolic CK isoforms, there are two mitochondrial creatine kinase isoenzymes, the ubiquitous and sarcomeric form. The functional entity of the latter two mitochondrial CK isoforms is an octamer consisting of four dimers each.
Abbr
CKMB, Native (Human)
Alias
CK-MB; CKMB; Creatine Kinase MB
Source
Human heart
Species
Human
Form
liquid
Concentration
> 0.5 mg/mL
Purification
> 70% (SDS-PAGE)
Stability
?20°C
Applications
The MB isoenzyme of creatine kinase (MBCK) can be used as a diagnostic marker for acute myocardial infarction.
Synonyms
CK-MB; CKMB; Creatine Kinase MB Fraction; Creatine Kinase MB
