Cat No.
NATE-0276
Description
Galactokinase catalyzes the phosphorylation of αD-galactose to produce galactose-1-phosphate as part of the Leloir pathway.
Abbr
GALK, Recombinant (Human)
Alias
GALK; GALK1; GALK2
Source
E. coli
Species
Human
Form
Supplied as a solution in 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 20% glycerol, 3 mM DTT and 10-200 mM imidazole.
Enzyme Commission Number
EC 2.7.1.6
Molecular Mass
42 kDa
Unit Definition
One unit will convert 1.0 picomole of galactose to galactose-1-phosphate per minute at pH 7.4 at 25°C.
Gene Name
GALK1 galactokinase 1 [Homo sapiens]
Synonyms
galactokinase (phosphorylating); ATP:D-galactose-1-phosphotransferase; EC 2.7.1.6; galactokinase; GALK; GALK1; GALK2
GeneID
2584
mRNA Refseq
NM_000154
Protein Refseq
NP_000145
MIM
604313
UniProt ID
P51570
Chromosome Location
17q23-q25
Pathway
Amino sugar and nucleotide sugar metabolism, organism-specific biosystem; Amino sugar and nucleotide sugar metabolism, conserved biosystem; Galactose catabolism, organism-specific biosystem; Galactose metabolism, organism-specific biosystem; Galactose metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem
Function
ATP binding; galactokinase activity; galactose binding; kinase activity; nucleotide binding; transferase activity
