Cat No.
NATE-1166
Description
HGPRT is a highly active enzyme that catalyzes the reversible transfer of the 5-phosphoribosyl group between α-D-5-phosphoribosyl-1-pyrophosphate (PRPP) and a purine base (hypoxanthine or guanine) to form a purine nucleotide IMP or GMP. The enzyme has been characterized for its affinity for natural substrates and velocity in forward and reverse directions.
Abbr
HGPRT, Recombinant (Human)
Alias
HGPRT
Source
E. coli
Species
Human
Enzyme Commission Number
EC 2.4.2.8
Bio-activity
> 1 Unit/mg protein
Molecular Mass
25kDa
Unit Definition
One unit of hypoxanthine-guanine phosphoribosyl transferase converts 1 μmole of hypoxanthine to IMP per minute at pH 8.8 at 25°C.
Synonyms
Hypoxanthine phosphoribosyltransferase; HGPRTase; HPRT; Hypoxanthine-guanine phosphoribosyltransferase; HGPRT; EC 2.4.2.8
