Cat No.
NATE-0646
Description
Pyrimidine nucleoside phosphorylase (PyNPase) is a glycosyltransferase that catalyzes the conversion of pyrimidine nucleoside and phosphate to a pyrimidine base and α-D-ribose 1-phosphate. PyNPase plays a significant role in breast cancer angiogenesis.
Abbr
PyNPase, Recombinant
Alias
PyNPase
Source
E. coli
Enzyme Commission Number
EC 2.4.2.2
Bio-activity
Type I, > 50 U/mL; Type II, > 1300 U/mL.
CAS No.
9055-35-0
Unit Definition
One unit will convert 1 μmole each of thymidine and phosphate to thymine and 2-deoxyribose 1-phosphate per minute at pH 7.4 and 25°C
Applications
Pyrimidine nucleoside phosphorylase (PyNPase) may be used as a marker to predict the malignant potential of breast cancer, especially lymph node metastasis. PyNPase is used to study breast cancer, specifically its role in angiogenesis. This product is recombinant and expressed in E. coli (> 50 U/mL).
Synonyms
Pyrimidine nucleoside phosphorylase; EC 2.4.2.2; Py-NPase; 9055-35-0; pdp (gene name); PyNPase
