Cat No.
NATE-0743
Description
α-Amylase is a protein enzyme EC 3.2.1.1 that hydrolyses alpha bonds of large, alpha-linked polysaccharides, such as starch and glycogen, yielding glucose and maltose. It is the major form of amylase found in Humans and other mammals. It is also present in seeds containing starch as a food reserve, and is secreted by many fungi.
Abbr
α-Amylase, Native (Human)
Alias
α-amylase
Source
Human saliva
Species
Human
Form
Lyophilized powder containing (NH4)2SO4 and sodium citrate
Enzyme Commission Number
EC 3.2.1.1
Bio-activity
1,000-3,000 units/mg protein; 300-1,500 units/mg protein
CAS No.
9001-19-8
Unit Definition
One unit will liberate 1.0 mg of maltose from starch in 3 min at pH 6.9 at 20°C.
Applications
α-Amylase is used to hydrolyze α bonds of α-linked polysaccharides, such as starch and glycogen. α-Amylase has been used in various plant studies, such as metabolism studies in Arabidopsis. α-Amylase from human saliva has been used to study the development of nutraceuticals, which may aid the treatment of diabetes and obesity.
Gene Name
AMY1A amylase, alpha 1A (salivary) [Homo sapiens]
Synonyms
glycogenase; αamylase, α-amylase; 1,4-α-D-glucan glucanohydrolase; EC 3.2.1.1; 9001-19-8; endoamylase; Taka-amylase A
GeneID
276
mRNA Refseq
NM_001008221
Protein Refseq
NP_001008222
MIM
104700
UniProt ID
P04745
Chromosome Location
1p21
Pathway
Carbohydrate digestion and absorption, organism-specific biosystem; Carbohydrate digestion and absorption, conserved biosystem; Digestion of dietary carbohydrate, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of carbohydrates, organism-specific biosystem; Salivary secretion, organism-specific biosystem
