Cat No.
NATE-0752
Description
Alpha-glucosidase is a glucosidase located in the brush border of the small intestine that acts upon 1,4-alpha bonds. This is in contrast to beta-glucosidase. Alpha-glucosidase breaks down starch and disaccharides to glucose. Maltase, a similar enzyme that cleaves maltose, is nearly functionally equivalent.
Abbr
α-Glucosidase, Native (Saccharomyces cerevisiae)
Alias
maltase
Species
Saccharomyces cerevisiae
Form
lyophilized powder.
Enzyme Commission Number
EC 3.2.1.20
Bio-activity
4-8 units/mg; > 10 units/mg protein (using p-nitrophenyl α-D-glucoside as substrate.)
CAS No.
9001-42-7
Molecular Mass
Mr ~63 kDa
Unit Definition
One unit will liberate 1.0 μmole of D-glucose from p-nitrophenyl α-D-glucoside per min at pH 6.8 at 37°C.
Applications
For the determination of α-amylase and the synthesis of various 1′-O-sucrose and 1-O-fructose esters. α-glucosidase is used for the determination of α-amylase and the synthesis of various 1′-O-sucrose and 1-O-fructose esters. It was also used in the measurement of glycosidase inhibition.
Gene Name
MAL12 alpha-glucosidase MAL12 [Saccharomyces cerevisiae S288c]; MAL32 alpha-glucosidase MAL32 [Saccharomyces cerevisiae S288c]
Synonyms
α-glucosidase; maltase; glucoinvertase; glucosidosucrase; maltase-glucoamylase; α-glucopyranosidase; glucosidoinvertase; α-D-glucosidase; α-glucoside hydrolase; α-1,4-glucosidase; EC 3.2.1.20; 9001-42-7
GeneID
853209; 852602
mRNA Refseq
NM_001181421; NM_001178647
Protein Refseq
NP_011808; NP_009858
UniProt ID
P53341; P38158
Chromosome Location
chromosome: VII; chromosome: II
Pathway
Amino acid transport across the plasma membrane, organism-specific biosystem; Galactose metabolism, conserved biosystem; Transmembrane transport of small molecules, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Starch and sucrose metabolism, conserved biosystem; Transmembrane transport of small molecules, organism-specific biosystem
Function
alpha-1,4-glucosidase activity; cation binding; maltose alpha-glucosidase activity; hydrolase activity; maltose alpha-glucosidase activity
