Cat No.
NATE-0774
Description
β--lactamase inactivates β-lactam antibiotics by breaking open the β-lactam ring.
Abbr
β-Lactamase, Native (Enterobacter cloacae)
Alias
β-lactamase
Species
Enterobacter cloacae
Form
Lyophilized powder containing sodium phosphate and sodium citrate buffer salts
Enzyme Commission Number
EC 3.5.2.6
Bio-activity
6-18 units/mg protein (using benzylpenicillin); 0.2-0.6 units/mg protein (using benzylpenicillin)
CAS No.
9073-60-3
Unit Definition
One unit will hydrolyze 1.0 μmole of benzylpenicillin per min at pH 7.0 at 25°C. This International Unit (using benzylpenicillin as substrate) is approximately equal to 600 Levy or 75 Pollock units.
Applications
β-lactamase is used to inactivate β-lactam antibiotics by breaking open the β-lactam ring. β-lactamase is used to study antibiotic resistance and resistance suppression1. This product is produced from Enterobacter cloacae.
Synonyms
β-lactamase; penicillinase; cephalosporinase; neutrapen; penicillin β-lactamase; exopenicillinase; ampicillinase; penicillin amido-β-lactamhydrolase; penicillinase I, II; β-lactamase I-III; β-lactamase A, B, C; β-lactamase AME I; cephalosporin-β-lactamase; EC 3.5.2.6; 9073-60-3
