Cat No.
NATE-0011
Description
Alpha 2-antiplasmin (or α2-antiplasmin or plasmin inhibitor) is a serine protease inhibitor (serpin) responsible for inactivating plasmin, an important enzyme that participates in fibrinolysis and degradation of various other proteins. This protein is encoded by the SERPINF2 gene.
Abbr
A2AP, Native (Human)
Alias
A2AP; AAP
Source
Human Plasma
Species
Human
Form
Lyophilized
Molecular Mass
63-70 kDa
Purification
> 95% (SDS-PAGE)
Specificity
> 5 IU/mg
Gene Name
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 [Homo sapiens]
Synonyms
Alpha-2 Antiplasmin; α2-antiplasmin; plasmin inhibitor; SERPINF2; A2AP; AAP; ALPHA-2-PI; API; PLI
GeneID
5345
mRNA Refseq
NM_000934
Protein Refseq
NP_000925
MIM
613168
UniProt ID
P08697
Chromosome Location
17pter-p12
Pathway
Blood Clotting Cascade, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Dissolution of Fibrin Clot, organism-specific biosystem; Hemostasis, organism-specific biosystem; Platelet activation, signaling and aggregation, organism-specific biosystem
Function
endopeptidase inhibitor activity; eukaryotic cell surface binding; protease binding; protein binding; protein homodimerization activity; serine-type endopeptidase inhibitor activity; serine-type endopeptidase inhibitor activity; serine-type endopeptidase inhibitor activity
