Cat No.
NATE-0947
Description
Alkaline Phosphatase (ALP) is a hydrolase enzyme responsible for removing phosphate groups in the 5- and 3- positions from many types of molecules, including nucleotides, proteins, and alkaloids. In humans, alkaline phosphatase is present in all tissues throughout the entire body, but is particularly concentrated in liver, bile duct, kidney, bone, and the placenta. The optimal pH for the enzyme activity is pH=10 in standard conditions.
Abbr
ALP, Native (Human)
Alias
ALP; ALKP
Source
Human Liver
Species
Human
Form
Liquid; Suspension in 3.1M ammonium sulfate with tris chloride, magnesium and zinc, pH 7.4.
Enzyme Commission Number
EC 3.1.3.1
Bio-activity
> 25 U/mL
CAS No.
9001-78-9
Appearance
Brown to tan suspension
Purification
Purified (Control Grade)
Unit Definition
One unit will catalyze the hydrolysis of one micromole of p-nitrophenyl phosphate per minute at 37°C and pH 10.35 in the presence of 2-amino-2-methyl-1-propanol.
Optimum pH
10
Stability
2 years
Synonyms
Alkaline phosphatase; ALP; ALKP; ALPase; Alk Phos; EC 3.1.3.1; Alkaline phosphomonoesterase; Glycerophosphatase; Phosphomonoesterase; HL-ALP
