Cat No.
NATE-0212
Description
Pancreatic elastase is a form of elastase that is produced in the acinar cells of the pancreas, initially produced as an inactive zymogen and later activated in the duodenum by trypsin. Elastases form a subfamily of serine proteases, characterized by a distinctive structure consisting of two beta barrel domains converging at the active site that hydrolyze amides and esters amongst many proteins in addition to elastin, a type of connective tissue that holds organs together. Pancreatic elastase 1 is a serine endopeptidase, a specific type of protease that has the amino acid serine at its active site.
Abbr
ELA1, Native (Pseudomonas aeruginosa)
Alias
ELA1
Species
Pseudomonas aeruginosa
Enzyme Commission Number
EC 3.4.24.26
Appearance
Lyophilized
Molecular Mass
33000
Purification
> 90% by SDS-PAGE
Specificity
> 250 units/mg protein
Unit Definition
One unit is defined as the amount of enzyme that will hydrolyze 1 μg insoluble elastin per h at 37°C.
Stability
Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 1 week at 4°Cor for up to 2 months at-20°C.
Synonyms
EC 3.4.21.36, pancreatopeptidase E; pancreatic elastase I; elastase; elaszym; serine elastase; elastase-1; pancreatopeptidase; ELA1
