Cat No.
NATE-1285
Description
GDA is an enzyme responsible for the hydrolytic deamination of guanine. Studies in rat ortholog suggest this gene plays a role in microtubule assembly. Multiple transcript variants encoding different isoforms have been found for this gene. Recombinant human GDA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Abbr
GDA, Recombinant (Human)
Alias
GDA
Source
E. coli
Species
Human
Form
1 mg/ml solution 20 mM Tris-HCl buffer (pH 8.0), 10% glycerol and 1 mM DTT.
Bio-activity
> 0.9 unit/ml
Appearance
Liquid
Molecular Mass
53 kDa (477 aa, 1-454 aa + His Tag)
Purification
> 90% determined by SDS-PAGE
Unit Definition
One unit will deaminate 1.0 μmole of guanine to xanthine per minute at pH 8.0 at 25°C.
Synonyms
Guanine deaminase; CYPIN; GUANASE; NEDASIN; guanine aminase; GAH; guanine aminohydrolase; GDA
