Cat No.
NATE-1176
Description
Alpha-galactosidase is a glycoside hydrolase enzyme that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. It is encoded by the GLA gene. Two recombinant forms of alpha-galactosidase are called agalsidase alfa (INN) and agalsidase beta (INN).
Abbr
GLA, Recombinant (Clostridium cellulolyticum)
Alias
GLA
Source
Clostridium cellulolyticum H10
Form
Supplied in 3.2 M ammonium sulphate
Enzyme Commission Number
EC 3.2.1.22
Bio-activity
186.7 U/mg
Concentration
561.85 U/ml
Molecular Mass
64179.5 Da
Purification
> 95 % as judged by SDS-PAGE
Unit Definition
One unit is defined as the amount of enzyme required to release 1 μmol of pNP per minute from pNP-α-D-galactopyranoside (1 mM) in 50 mM sodium phosphate buffer, pH 6.0, at 40°C, and using an extinction coefficient of 18000 M-1 cm-1.
Optimum pH
6
Synonyms
Alpha-Galactosidase; Galactosidase; EC 3.2.1.22; GLA; GALA; melibiase; α-D-galactosidase; α-galactosidase A; α-galactoside galactohydrolase
