Cat No.
NATE-0329
Description
β-glucuronidase catalyzes the breakdown of complex carbohydrates. In humans it converts conjugated bilirubin into the unconjugated form, making bilirubin suitable for reabsorption.
Abbr
GUSB, Native (Bovine)
Alias
GUSB
Source
Bovine liver
Species
Bovine
Enzyme Commission Number
EC 3.2.1.31
Bio-activity
Type B-10, ~10,000 units/mg solid; Type B-1, > 1,000,000 units/g solid; Type B-3, > 2,000,000 units/g solid
CAS No.
9001-45-0
Unit Definition
One unit will liberate 1.0 μg of phenolphthalein from phenolphthalein glucuronide per hr at 37°C at pH 5.0 (30 min assay).
Applications
β-glucuronidase is used as a reporter gene in GUS assays to monitor gene expression.
Gene Name
GUSB
Synonyms
β-glucuronide glucuronohydrolase glucuronidase; exo-β-D-glucuronidase; ketodase; EC 3.2.1.31; 9001-45-0; β-D-glucuronoside glucuronosohydrolase; GUSB
GeneID
515687
mRNA Refseq
NM_001083436.1
Protein Refseq
NP_001076905.1
UniProt ID
A3KMY8
Chromosome Location
25
Pathway
Ascorbate biosynthesis, animals, glucose-1P => ascorbate, organism-specific biosystem (from KEGG) Ascorbate biosynthesis, animals, glucose-1P => ascorbate, conserved biosystem (from KEGG) Chondroitin sulfate degradation, organism-specific biosystem (from KEGG)
Function
AnxA6 is a novel receptor that mediates the endocytosis of bovine beta-glucuronidase.
