Cat No.
NATE-0348
Description
Hyaluronidase degrades hyaluronan and has been found to be inappropriately regulated during cancer progression. These enzymes randomly cleave β-N-acetylhexosamine-[1→4] glycosidic bonds in hyaluronic acid, chondroitin, and chondroitin sulfates.
Abbr
Hyaluronidase, Native (Sheep)
Source
Sheep testes
Species
Sheep
Form
Type I, lyophilized powder; Type II, Lyophilized powder containing lactose.
Enzyme Commission Number
EC 3.2.1.35
Bio-activity
Type I, > 1,500 units/mg solid; Type II, > 300 units/mg solid.
CAS No.
37326-33-3
Molecular Mass
mol wt 55 kDa
Unit Definition
One unit will cause a change in A600 of 0.330 per minute at pH 5.7 at 37°C in a 2.0 ml reaction mixture (45 minute assay).
Synonyms
hyaluronoglucosaminidase; hyaluronidase; hyaluronoglucosidase; chondroitinase; chondroitinase I; hyaluronate 4-glycanohydrolase; EC 3.2.1.35; 37326-33-3
