Cat No.
NATE-0353
Description
Pyrophosphatase (or inorganic pyrophosphatase) is an enzyme (EC 3.6.1.1) that catalyzes the conversion of one molecule of pyrophosphate to two phosphate ions. This is a highly exergonic reaction, and therefore can be coupled to unfavorable biochemical transformations in order to drive these transformations to completion. The functionality of this enzyme plays a critical role in lipid metabolism (including lipid synthesis and degradation), calcium absorption and bone formation, and DNA synthesis,as well as other biochemical transformations.
Abbr
Inorganic pyrophosphatase, Native (Bacillus stearothermophilus)
Species
Bacillus stearothermophilus
Form
lyophilized powder
Enzyme Commission Number
EC 3.6.1.1
Bio-activity
15-25 units/mg protein (biuret)
CAS No.
9024-82-2
Unit Definition
One unit will liberate 1.0 μmole of inorganic orthophosphate per min at pH 9.0 at 50°C.
Applications
Inorganic pyrophosphatase (PPase) is a ubiquitous enzyme catalyzing the reaction PPi + H2O → 2Pi. It plays an important role in protein, RNA, and DNA synthesis.
Synonyms
Pyrophosphate phosphohydrolase; inorganic pyrophosphatase; EC 3.6.1.1; 9024-82-2; iphosphate phosphohydrolase
