Cat No.
CEI-1144
Description
AZD-26 inhibits the phosphorylation of Thr308 on AKT in BT474 cells with IC50 of 0.422nM. It also inhibits the phosphorylation of Ser473 on AKT in MDAMB468 cells with IC50 of 0.322nM.
Abbr
AZD-26(AKT1)
Alias
AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA
Synonyms
AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA
CAS No.
1357158-81-6
IC50
0.422nM, 0.322nM
Targets
Thr308/AKT, Ser473/AKT
Chemical Name
6-(4-(1-aminocyclobutyl)phenyl)-5-phenylnicotinamide
M.Wt
343.42
Purity
> 95%
Solubility
DMSO > 112mg/mL Water >1mg/mL Ethanol > 4mg/mL
Storage
4 centigrade
Stability
2 years -20 centigrade Powder
1 month -4 centigrade in DMSO
More than one month -80 centigrade in DMSO
