Cat No.
CEI-0408
Description
PFI-1 is a BET bromodomain inhibitor that exhibits inhibitory activity at BRD2 and BRD4. In an AlphaScreen assay it has been shown to inhibit BRD2 bromodomain 2 and BRD4 bromodomain 1 with IC50 values of 98 nM and 0.22 μM, respectively.
Product_Overview
A potent BET bromodomain inhibitor
Targets
BRD2, BRD4
Chemical Name
2-?Methoxy-?N-?(3-?methyl-?2-?oxo-?1,?2,?3,?4-?tetrahydroquinazolin-?6-?yl)benzenesulfonamide
M.Wt
358.48
Purity
>98%
Appearance
Crystalline solid
Solubility
DMSO
Storage
-20 centigrade
Shipping Conditions
Gel Pack
Handling
Protect from light and moisture
Usage
For Research Use Only! Not For Use in Humans.
