Cat No.
CEI-0966
Description
Potent and selective inhibitor of Bruton's tyrosine kinase (BTK). Inhibits recombinant BTK with an IC50 = 2.5 uM and has no activity at other protein kinases (including JAK1, JAK3, HCK, EGFR kinase and insulin receptor kinase) at concentrations up to 300 uM.
Abbr
LFM-A13(BTK)
Alias
2-Cyano-N-(2, 5-dibromophenyl)-3-hydroxy-2-butenamide
Synonyms
2-Cyano-N-(2,5-dibromophenyl)-3-hydroxy-2-butenamide
CAS No.
62004-35-7
Product_Overview
BTK Inhibitor
Targets
BTK
M.Wt
360.0
Melting Point
145-146oC
Purity
98% (TLC: 2:8 CH3OH:CH2Cl2; Rf=0.53); NMR (Conforms)
Appearance
Yellow powder
Solubility
DMSO (10 mg/ml) and ethanol (15 mg/ml)
