Cat No.
CEI-0424
Description
A synthetic peptide that irreversibly inhibits ICE (interleukin-1β converting enzyme, Ki = 0.76 nM) activity. YVAD is the specific recognition sequence for ICE/caspase-1. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).
Alias
Z-YVAD-FMK, Caspase-1 Inhibitor (fluoromethylketone)
Synonyms
Z-YVAD-FMK, Caspase-1 Inhibitor (fluoromethylketone)
Product_Overview
Caspase-1 inhibitor
Targets
Caspase-1
M.Wt
223.28
Purity
>98% by HPLC
Appearance
Yellow solid
Solubility
DMSO (~ 5 mg/ml)
Storage
-20 centigrade
Shipping Conditions
Gel pack
Handling
Protect from air and moisture
Usage
For Research Use Only! Not For Use in Humans.
