Cat No.
CEI-0441
Description
A synthetic peptide that irreversibly inhibits activity of caspase-8 and related caspases and blocks apoptosis. The inhibitor is designed as a methyl ester to enhance cell permeability. The conjugation with biotin allows detection of activated caspases in conjunction with avidin-tags. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).
Alias
Biotin-IETD-FMK, IETD-FMK, Biotin-
Synonyms
Biotin-IETD-FMK, IETD-FMK, Biotin-
Product_Overview
A Caspase-8 inhibitor
Targets
CASP8
M.Wt
489.4
Purity
>98% by HPLC
Appearance
White to off-white solid
Solubility
DMSO (~ 15 mg/ml) or Ethanol (~ 10 mg/ml)
Storage
-20 centigrade
Shipping Conditions
Gel pack
Handling
Protect from air and light
Usage
For Research Use Only! Not For Use in Humans.
