Cat No.
CEI-1153
Description
PD 0332991 is a highly selective inhibitor of CDK4/cyclin D1 and CDK6/cyclin D2 with IC50 of 11 nM and 16 nM, respectively.
Abbr
PD-0332991 HCl(CDK4, CCND1, CDK6, CCND2)
Alias
CMM3, PSK-J3
Synonyms
CMM3, PSK-J3
IC50
11 nM, 16 nM
Targets
CDK4/cyclin D1, CDK6/cyclin D2
Chemical Name
6-acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one
M.Wt
520.45
Purity
> 95%
Storage
4 centigrade
