Cat No.
CEI-1002
Description
(R)-MG132 is a potent, cell permeable and reversible inhibitor of proteasomes. It can inhibit proteasome activity in lysates of J558L multiple myeloma cells and EMT6 breast cancer cells. In comparison to (S)-MG132, the (R)-MG132 stereoisomer is a more effective inhibitor of chymotrypsin-like (ChTL), trypsin-like (TL), and peptidylglutamyl peptide hydrolyzing proteasome (PGPH) activities.
Abbr
(R)-MG132(ChTL, TLa, PGPH)
CAS No.
1211877-36-9
IC50
0.22 μM, 34.4 μM, 2.95 μM
Targets
ChTL, TLa, PGPH
M.Wt
475.6
Purity
>98%
Appearance
A crystalline solid.
Storage
Store at or below -20 centigrade for up to two years.