Cat No.
CEI-0416
Description
A potent, cell-permeable, and selective inhibitor of calpain and cathepsin B (Ki values are 10 and 25 nM respectively). MDL 28170 does not inhibit trypsin-like serine proteases. Rapidly penetrates the blood-brain barrier following systemic administration and displays neuroprotective effects in vivo. Modulates the formation of Aβ formation by inhibiting the formation of intermediate Aβ46 and protecting Aβ from degradation.
Alias
Z-Val-Phe-CHO; Carbobenzoxy-valinyl-phenylalaninal; Calpain Inhibitor III
Synonyms
Z-Val-Phe-CHO; Carbobenzoxy-valinyl-phenylalaninal; Calpain Inhibitor III
CAS No.
88191-84-8
Product_Overview
A potent calpain and cathepsin B inhibitor
Targets
calpain, cathepsin B
M.Wt
628.81
Purity
>98% by HPLC
Appearance
White to off-white solid
Solubility
DMSO
Storage
-20 centigrade
Shipping Conditions
Gel pack
Handling
Protect from air and moisture
Usage
For Research Use Only! Not For Use in Humans.
